Top 40 InterPro Domains in the Ensembl Database

No.

Interpro name	Number of genes	Number of Ensembl hits	No.	Interpro name	Number of genes	Number of Ensembl hits
1	IPR000276 GPCR, rhodopsin-like	1282	35568	21	IPR000048 IQ calmodulin-binding region	84	1772
2	IPR000694 Proline-rich region	961	11893	22	IPR001254 Peptidase S1 and S6, chymotrypsin/Hap	81	877
3	IPR000719 Protein kinase, core	329	5558	23	IPR000315 Zinc finger, B-box	75	1370
4	IPR003596 Immunoglobulin V-set, subgroup	323	4129	24	IPR001128 Cytochrome P450	72	1920
5	IPR000504 RNA recognition motif, RNP-1	216	2003	25	IPR000742 EGF-like, type 3	67	1900
6	IPR001680 WD40 repeat	187	3782	26	IPR003598 Immunoglobulin subtype 2	67	1154
7	IPR000533 Tropomyosin	180	1492	27	IPR000372 Leucine-rich repeat, cysteine-rich flanking region, N-terminal	66	1912
8	IPR000210 BTB/POZ-like	174	4358	28	IPR000219 Dbl homology (DH) domain	64	922
9	IPR001806 Ras GTPase	140	1959	29	IPR007087 Zinc finger, C2H2-type	64	897
10	IPR001781 Zinc finger, LIM-type	139	10134	30	IPR001092 Basic helix-loop-helix dimerisation region bHLH	64	334
11	IPR001841 Zinc finger, RING-type	139	1015	31	IPR000198 RhoGAP	62	721
12	IPR000008 C2 calcium-dependent membrane targeting	129	2550	32	IPR001304 C-type lectin	61	610
13	IPR001909 Krueppel-associated box	128	6402	33	IPR001478 PDZ/DHR/GLGF	60	630
14	IPR000047 Helix-turn-helix motif, lambda-like repressor	127	1910	34	IPR000215 Protease inhibitor I4, serpin	60	593
15	IPR000104 Antifreeze protein, type I	119	1537	35	IPR007086 Zinc finger, C2H2-subtype	57	1900
16	IPR002110 Ankyrin	117	2431	36	IPR000357 HEAT	57	464
17	IPR001611 Leucine-rich repeat	102	1335	37	IPR000108 Neutrophil cytosol factor 2	57	2271
18	IPR000152 Aspartic acid and asparagine hydroxylation site	87	7640	38	IPR001993 Mitochondrial substrate carrier	55	1025
19	IPR002048 Calcium-binding EF-hand	87	784	39	IPR002198 Short-chain dehydrogenase/reductase SDR	53	796
20	IPR001440 Tetratricopeptide TPR-1	86	1825	40	IPR001461 Peptidase A1	52	517

View top 500 InterPro hits (large table)

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