Top 500 InterPro Domains in the Ensembl Database

No.

Interpro name	Number of genes	Number of Ensembl hits	No.	Interpro name	Number of genes	Number of Ensembl hits
1	IPR000276 GPCR, rhodopsin-like	1282	35568	251	IPR000648 Oxysterol-binding protein	12	71
2	IPR000694 Proline-rich region	961	11893	252	IPR000712 Apoptosis regulator Bcl-2, BH	12	192
3	IPR000719 Protein kinase, core	329	5558	253	IPR005821 Ion transport	12	25
4	IPR003596 Immunoglobulin V-set, subgroup	323	4129	254	IPR001007 von Willebrand factor, type C	12	319
5	IPR000504 RNA recognition motif, RNP-1	216	2003	255	IPR003689 Zinc/iron permease	12	16
6	IPR001680 WD40 repeat	187	3782	256	IPR003034 DNA-binding SAP	12	64
7	IPR000533 Tropomyosin	180	1492	257	IPR005024 Snf7	12	12
8	IPR000210 BTB/POZ-like	174	4358	258	IPR000327 POU-specific	12	230
9	IPR001806 Ras GTPase	140	1959	259	IPR001111 Transforming growth factor beta (TGFb), N-terminal	12	104
10	IPR001781 Zinc finger, LIM-type	139	10134	260	IPR001211 Phospholipase A2, eukaryotic	12	143
11	IPR001841 Zinc finger, RING-type	139	1015	261	IPR001309 Peptidase C14, ICE, catalytic subunit p20	12	198
12	IPR000008 C2 calcium-dependent membrane targeting	129	2550	262	IPR000876 Ribosomal protein S4e	12	109
13	IPR001909 Krueppel-associated box	128	6402	263	IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase	12	119
14	IPR000047 Helix-turn-helix motif, lambda-like repressor	127	1910	264	IPR001589 Actinin-type, actin-binding, conserved site	12	343
15	IPR000104 Antifreeze protein, type I	119	1537	265	IPR001969 Peptidase aspartic, active site	12	67
16	IPR002110 Ankyrin	117	2431	266	IPR005828 General substrate transporter	12	52
17	IPR001611 Leucine-rich repeat	102	1335	267	IPR000721 Retroviral nucleocapsid protein Gag	12	149
18	IPR000152 Aspartic acid and asparagine hydroxylation site	87	7640	268	IPR001699 Transcription factor, T-box	12	181
19	IPR002048 Calcium-binding EF-hand	87	784	269	IPR001159 Double-stranded RNA binding	12	111
20	IPR001440 Tetratricopeptide TPR-1	86	1825	270	IPR003594 ATP-binding region, ATPase-like	12	78
21	IPR000048 IQ calmodulin-binding region	84	1772	271	IPR006025 Peptidase M, neutral zinc metallopeptidases, zinc-binding site	12	116
22	IPR001254 Peptidase S1 and S6, chymotrypsin/Hap	81	877	272	IPR000223 Peptidase S26A, signal peptidase I	12	122
23	IPR000315 Zinc finger, B-box	75	1370	273	IPR000300 Inositol polyphosphate related phosphatase	12	105
24	IPR001128 Cytochrome P450	72	1920	274	IPR011046 WD40 repeat-like	12	20
25	IPR000742 EGF-like, type 3	67	1900	275	IPR003191 Guanylate-binding protein, C-terminal	12	42
26	IPR003598 Immunoglobulin subtype 2	67	1154	276	IPR007237 CD20/IgE Fc receptor beta subunit	11	13
27	IPR000372 Leucine-rich repeat, cysteine-rich flanking region, N-terminal	66	1912	277	IPR001064 Beta and gamma crystallin	11	183
28	IPR000219 Dbl homology (DH) domain	64	922	278	IPR004344 Tubulin-tyrosine ligase	11	11
29	IPR007087 Zinc finger, C2H2-type	64	897	279	IPR000867 Insulin-like growth factor-binding protein, IGFBP	11	179
30	IPR001092 Basic helix-loop-helix dimerisation region bHLH	64	334	280	IPR002052 N-6 adenine-specific DNA methylase, conserved site	11	235
31	IPR000198 RhoGAP	62	721	281	IPR006670 Cyclin	11	41
32	IPR001304 C-type lectin	61	610	282	IPR004254 Hly-III related proteins	11	17
33	IPR001478 PDZ/DHR/GLGF	60	630	283	IPR000517 Ribosomal protein L30, core	11	45
34	IPR000215 Protease inhibitor I4, serpin	60	593	284	IPR000695 H+ transporting ATPase, proton pump	11	299
35	IPR007086 Zinc finger, C2H2-subtype	57	1900	285	IPR002999 Tudor	11	83
36	IPR000357 HEAT	57	464	286	IPR001734 Na+/solute symporter	11	53
37	IPR000108 Neutrophil cytosol factor 2	57	2271	287	IPR012336 Thioredoxin-like fold	11	24
38	IPR001993 Mitochondrial substrate carrier	55	1025	288	IPR000904 SEC7-like	11	91
39	IPR002198 Short-chain dehydrogenase/reductase SDR	53	796	289	IPR001958 Tetracycline resistance protein, TetA	11	87
40	IPR001461 Peptidase A1	52	517	290	IPR016196 MFS general substrate transporter	11	12
41	IPR000436 Sushi/SCR/CCP	51	1747	291	IPR000270 Octicosapeptide/Phox/Bem1p	11	117
42	IPR000886 Endoplasmic reticulum, targeting sequence	51	465	292	IPR000331 Rap/ran-GAP	11	58
43	IPR000225 Armadillo	51	874	293	IPR001079 Galectin, galactose-binding lectin	11	56
44	IPR000558 Histone H2B	50	571	294	IPR003409 MORN motif	11	148
45	IPR000626 Ubiquitin	49	346	295	IPR000975 Interleukin-1	11	180
46	IPR001849 Pleckstrin-like	47	288	296	IPR000555 Mov34/MPN/PAD-1	11	36
47	IPR001810 Cyclin-like F-box	47	230	297	IPR006055 Exonuclease	11	40
48	IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type	46	1298	298	IPR001464 Annexin	11	429
49	IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2	46	290	299	IPR000222 Protein phosphatase 2C, manganese/magnesium aspartate binding site	11	83
50	IPR016024 Armadillo-type fold	46	54	300	IPR003091 Voltage-dependent potassium channel	11	130
51	IPR000637 HMG-I and HMG-Y, DNA-binding	46	723	301	IPR001590 Peptidase M12B, ADAM/reprolysin	11	243
52	IPR001356 Homeobox	46	520	302	IPR015590 Aldehyde dehydrogenase	11	39
53	IPR001039 MHC class I, alpha chain, alpha1 and alpha2	46	324	303	IPR001346 Interferon regulatory factor	10	94
54	IPR002190 MAGE protein	45	146	304	IPR004299 Membrane bound O-acyl transferase, MBOAT	10	14
55	IPR000767 Disease resistance protein	44	799	305	IPR001427 Pancreatic ribonuclease	10	82
56	IPR001664 Intermediate filament protein	43	478	306	IPR006594 LisH dimerisation motif	10	62
57	IPR001190 Speract/scavenger receptor	43	1534	307	IPR000333 Activin type II receptor	10	158
58	IPR001452 Src homology-3	42	724	308	IPR001494 Importin-beta, N-terminal	10	45
59	IPR001888 Transposase, type 1	41	58	309	IPR000308 14-3-3 protein	10	98
60	IPR000884 Thrombospondin, type I	40	1050	310	IPR000651 Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal	10	167
61	IPR000169 Peptidase, cysteine peptidase active site	40	1336	311	IPR004853 Protein of unknown function DUF250	10	19
62	IPR002126 Cadherin	40	2492	312	IPR000217 Tubulin	10	250
63	IPR000159 Ras-association	40	485	313	IPR001305 Heat shock protein DnaJ, cysteine-rich region	10	157
64	IPR000477 RNA-directed DNA polymerase (reverse transcriptase)	39	390	314	IPR001251 Cellular retinaldehyde-binding/triple function, C-terminal	10	38
65	IPR000571 Zinc finger, CCCH-type	39	250	315	IPR000734 Lipase	10	172
66	IPR000980 SH2 motif	39	479	316	IPR001060 Cdc15/Fes/CIP4	10	88
67	IPR000299 Band 4.1, N-terminal	38	635	317	IPR000601 PKD	10	131
68	IPR001140 ABC transporter, transmembrane region	38	628	318	IPR002952 Eggshell protein	10	72
69	IPR000195 RabGAP/TBC	38	279	319	IPR000731 Sterol-sensing 5TM box	10	89
70	IPR001623 Heat shock protein DnaJ, N-terminal	38	383	320	IPR001293 Zinc finger, TRAF-type	10	157
71	IPR000471 Interferon alpha, beta and delta	38	270	321	IPR000089 Biotin/lipoyl attachment	10	147
72	IPR000248 Angiotensin II receptor	37	1482	322	IPR015894 Guanylate-binding protein, N-terminal	10	17
73	IPR008253 Marvel	37	121	323	IPR004072 Vomeronasal receptor, type 1	10	123
74	IPR000608 Ubiquitin-conjugating enzyme, E2	37	238	324	IPR000836 Phosphoribosyltransferase	10	34
75	IPR000449 Ubiquitin-associated/translation elongation factor EF1B, N-terminal	37	557	325	IPR008405 Apolipoprotein L	10	16
76	IPR001650 DNA/RNA helicase, C-terminal	36	365	326	IPR006612 Zinc finger, C2CH-type	10	37
77	IPR003593 AAA+ ATPase, core	36	150	327	IPR001345 Phosphoglycerate/bisphosphoglycerate mutase	10	90
78	IPR000232 Heat shock factor (HSF)-type, DNA-binding	34	63	328	IPR008957 Fibronectin, type III-like fold	10	16
79	IPR001752 Kinesin, motor region	34	281	329	IPR001239 Proteinase inhibitor I1, Kazal metazoa	10	158
80	IPR001222 Zinc finger, TFIIS-type	33	2061	330	IPR000910 High mobility group box, HMG1/HMG2	10	84
81	IPR000340 Protein-tyrosine phosphatase, dual specificity	33	297	331	IPR004367 Cyclin, C-terminal	10	90
82	IPR000595 Cyclic nucleotide-binding	33	545	332	IPR004365 Nucleic acid binding, OB-fold, tRNA/helicase-type	10	39
83	IPR003439 ABC transporter-like	33	226	333	IPR003072 Orphan nuclear receptor, NOR1 type	10	42
84	IPR003656 Zinc finger, BED-type predicted	33	1185	334	IPR009886 HCaRG	10	14
85	IPR002164 Nucleosome assembly protein (NAP)	33	38	335	IPR000286 Histone deacetylase superfamily	9	89
86	IPR000480 Glutelin	32	387	336	IPR000577 Carbohydrate kinase, FGGY	9	36
87	IPR000135 High mobility group box, HMG1/HMG2, subgroup	32	453	337	IPR000469 G-protein alpha subunit, group 12	9	219
88	IPR002035 von Willebrand factor, type A	31	393	338	IPR006662 Thioredoxin-related	9	49
89	IPR000330 SNF2-related	31	419	339	IPR000602 Glycoside hydrolase, family 38, core	9	44
90	IPR001660 Sterile alpha motif SAM	31	411	340	IPR006089 Acyl-CoA dehydrogenase, conserved site	9	87
91	IPR000301 CD9/CD37/CD63 antigen	31	265	341	IPR000591 Pleckstrin/ G-protein, interacting region	9	118
92	IPR001395 Aldo/keto reductase	31	371	342	IPR000269 Copper amine oxidase	9	153
93	IPR000863 Sulphotransferase	30	48	343	IPR000190 AT1 angiotensin II receptor	9	370
94	IPR000175 Sodium:neurotransmitter symporter	30	440	344	IPR000764 Uridine kinase	9	130
95	IPR000873 AMP-dependent synthetase and ligase	30	161	345	IPR001024 Lipoxygenase, LH2	9	197
96	IPR000164 Histone H3	30	318	346	IPR004045 Glutathione S-transferase, N-terminal	9	51
97	IPR001214 SET	30	489	347	IPR001134 Netrin, C-terminal	9	161
98	IPR005135 Endonuclease/exonuclease/phosphatase	29	124	348	IPR001811 Small chemokine, interleukin-8-like	9	60
99	IPR001855 Beta defensin	29	63	349	IPR001107 Band 7 protein	9	58
100	IPR001005 SANT, DNA-binding	29	346	350	IPR000817 Prion protein	9	112
101	IPR000014 PAS	28	504	351	IPR000768 NAD:arginine ADP-ribosyltransferase, ART	9	93
102	IPR000306 Zinc finger, FYVE-type	28	543	352	IPR004087 K Homology	9	83
103	IPR003309 Transcriptional regulator SCAN	28	592	353	IPR001564 Nucleoside diphosphate kinase, core	9	132
104	IPR002119 Histone H2A	28	252	354	IPR001176 1-aminocyclopropane-1-carboxylate synthase	9	77
105	IPR000629 RNA helicase, ATP-dependent, DEAD-box, conserved site	27	259	355	IPR000538 Link	9	400
106	IPR003604 Zinc finger, U1-type	27	539	356	IPR001753 Crotonase, core	9	36
107	IPR000073 Alpha/beta hydrolase fold-1	27	205	357	IPR001373 Cullin, N-terminal region	9	57
108	IPR000342 Regulator of G protein signalling	26	353	358	IPR000403 Phosphatidylinositol 3- and 4-kinase, catalytic	9	75
109	IPR001757 ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter	26	276	359	IPR002109 Glutaredoxin	9	61
110	IPR001632 G-protein, beta subunit	26	867	360	IPR005123 2OG-Fe(II) oxygenase	9	34
111	IPR000253 Forkhead-associated	26	249	361	IPR007667 Hypoxia induced protein conserved region	9	9
112	IPR000203 GPS	26	843	362	IPR009053 Prefoldin	9	20
113	IPR000408 Regulator of chromosome condensation, RCC1	26	482	363	IPR000192 Aminotransferase, class V/Cysteine desulphurase	9	37
114	IPR001683 Phox-like	25	174	364	IPR001619 Sec1-like protein	9	19
115	IPR000082 SEA	25	551	365	IPR001012 UBX	9	52
116	IPR000488 Death	25	370	366	IPR003590 Leucine-rich repeat, ribonuclease inhibitor subtype	9	44
117	IPR000566 Lipocalin-related protein and Bos/Can/Equ allergen	25	437	367	IPR000998 MAM	9	206
118	IPR000467 D111/G-patch	24	259	368	IPR007052 CS domain	9	34
119	IPR000953 Chromo domain	24	191	369	IPR002913 Lipid-binding START	9	30
120	IPR000324 Vitamin D receptor	24	803	370	IPR001436 Alpha crystallin/Heat shock protein	9	79
121	IPR000010 Proteinase inhibitor I25, cystatin	24	129	371	IPR000106 Protein-tyrosine phosphatase, low molecular weight	9	92
122	IPR000418 Ets	23	278	372	IPR003406 Glycosyl transferase, family 14	9	13
123	IPR003961 Fibronectin, type III	23	176	373	IPR001507 Endoglin/CD105 antigen	8	70
124	IPR000086 NUDIX hydrolase, core	23	126	374	IPR000072 Platelet-derived growth factor (PDGF)	8	60
125	IPR000727 Target SNARE coiled-coil region	22	133	375	IPR000329 Uteroglobin-like	8	69
126	IPR000971 Globin, subset	22	360	376	IPR001902 Sulphate anion transporter	8	60
127	IPR000003 Retinoid X receptor	22	706	377	IPR000994 Peptidase M24, catalytic core	8	68
128	IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular	22	143	378	IPR000641 CbxX/CfqX	8	59
129	IPR001870 B302, (SPRY)-like	22	346	379	IPR002076 GNS1/SUR4 membrane protein	8	17
130	IPR000772 Ricin B lectin	22	225	380	IPR002909 Cell surface receptor IPT/TIG	8	79
131	IPR000158 Cell division protein FtsZ, N-terminal	22	990	381	IPR001377 Ribosomal protein S6e	8	19
132	IPR000313 PWWP	22	290	382	IPR007593 Interferon-induced transmembrane protein	8	9
133	IPR000381 Inhibin, beta B subunit	22	338	383	IPR006052 Tumor Necrosis Factor	8	44
134	IPR001509 NAD-dependent epimerase/dehydratase	22	242	384	IPR000409 Beige/BEACH	8	140
135	IPR000233 Cadherin cytoplasmic region	22	990	385	IPR001606 AT-rich interaction region	8	102
136	IPR000795 Protein synthesis factor, GTP-binding	22	229	386	IPR001003 MHC class II, alpha chain, N-terminal	8	68
137	IPR001951 Histone H4	22	230	387	IPR000539 Frizzled protein	8	38
138	IPR000261 EPS15 homology (EH)	22	432	388	IPR007130 Diacylglycerol acyltransferase	8	9
139	IPR001125 Recoverin	22	354	389	IPR001791 Laminin G	8	239
140	IPR001496 SOCS protein, C-terminal	22	430	390	IPR002553 Clathrin/coatomer adaptor, adaptin-like, N-terminal	8	72
141	IPR001751 S100/CaBP-9k-type, calcium binding	21	159	391	IPR000426 Proteasome alpha-subunit, conserved site	8	17
142	IPR000500 Connexins	21	273	392	IPR011701 Major facilitator superfamily MFS-1	8	22
143	IPR007114 Major facilitator superfamily	21	71	393	IPR005334 Tctex-1	8	8
144	IPR000157 Toll-Interleukin receptor	21	457	394	IPR000322 Glycoside hydrolase, family 31	8	36
145	IPR001163 Like-Sm ribonucleoprotein, core	21	65	395	IPR001310 Histidine triad (HIT) protein	8	62
146	IPR001991 Sodium:dicarboxylate symporter	21	206	396	IPR000803 Facilitated glucose transporter	8	192
147	IPR001594 Zinc finger, DHHC-type	21	93	397	IPR001881 EGF-like calcium-binding	8	268
148	IPR000182 GCN5-related N-acetyltransferase	20	84	398	IPR002049 EGF-like, laminin	8	551
149	IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase	20	74	399	IPR007632 Protein of unknown function DUF590	8	12
150	IPR002073 3'5'-cyclic nucleotide phosphodiesterase	20	322	400	IPR000174 Interleukin-8 receptor	8	500
151	IPR001627 Semaphorin/CD100 antigen	20	269	401	IPR000058 Zinc finger, AN1-type	8	58
152	IPR001766 Fork head transcription factor	20	187	402	IPR000173 Glyceraldehyde 3-phosphate dehydrogenase	8	86
153	IPR008331 Ferritin and Dps	20	87	403	IPR000542 Acyltransferase ChoActase/COT/CPT	8	23
154	IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site	20	218	404	IPR002108 Actin-binding, cofilin/tropomyosin type	8	47
155	IPR001715 Calponin-like actin-binding	20	137	405	IPR000243 Peptidase T1A, proteasome beta-subunit	8	47
156	IPR000483 Cysteine-rich flanking region, C-terminal	20	488	406	IPR003140 Phospholipase/carboxylesterase	8	9
157	IPR000585 Hemopexin	20	405	407	IPR001209 Ribosomal protein S14	8	13
158	IPR001965 Zinc finger, PHD-type	20	505	408	IPR006652 Kelch repeat type 1	8	100
159	IPR000679 Zinc finger, GATA-type	20	940	409	IPR000866 Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen	8	29
160	IPR001839 Transforming growth factor beta	20	106	410	IPR000020 Anaphylatoxin/fibulin	8	316
161	IPR005816 Secreted growth factor Wnt protein	19	213	411	IPR003653 Peptidase C48, SUMO/Sentrin/Ubl1	8	20
162	IPR004843 Metallophosphoesterase	19	144	412	IPR001375 Peptidase S9, prolyl oligopeptidase active site region	8	52
163	IPR000759 Adrenodoxin reductase	19	511	413	IPR002000 Lysosome-associated membrane glycoprotein (Lamp)/CD68	8	43
164	IPR004000 Actin/actin-like	19	194	414	IPR002091 Aromatic amino acid permease	8	42
165	IPR002223 Proteinase inhibitor I2, Kunitz metazoa	19	306	415	IPR002129 Pyridoxal phosphate-dependent decarboxylase	8	70
166	IPR000832 GPCR, family 2, secretin-like	19	482	416	IPR002345 Lipocalin	8	27
167	IPR003006 Immunoglobulin/major histocompatibility complex, conserved site	19	349	417	IPR001102 Transglutaminase, N-terminal	8	112
168	IPR001390 Gamma-aminobutyric-acid A receptor, alpha subunit	19	504	418	IPR000545 Lactalbumin	8	201
169	IPR003597 Immunoglobulin C1-set	19	160	419	IPR000911 Ribosomal protein L11	7	33
170	IPR002293 Amino acid/polyamine transporter I	19	47	420	IPR004217 Zinc finger, Tim10/DDP-type	7	7
171	IPR001526 CD59 antigen	18	60	421	IPR003100 Argonaute and Dicer protein, PAZ	7	38
172	IPR000834 Peptidase M14, carboxypeptidase A	18	130	422	IPR001952 Alkaline phosphatase	7	66
173	IPR002229 Blood group Rhesus C/E and D polypeptide	18	151	423	IPR000494 EGF receptor, L domain	7	195
174	IPR001164 Arf GTPase activating protein	18	308	424	IPR000005 Helix-turn-helix, AraC type	7	12180
175	IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase	18	41	425	IPR001147 Ribosomal protein L21e	7	18
176	IPR001073 Complement C1q protein	18	202	426	IPR006187 Claudin	7	24
177	IPR001202 WW/Rsp5/WWP	18	281	427	IPR003890 MIF4G-like, type 3	7	34
178	IPR000033 Low-density lipoprotein receptor, YWTD repeat	18	1950	428	IPR001553 RecA bacterial DNA recombination	7	36
179	IPR000079 High mobility group protein HMG14 and HMG17	18	175	429	IPR002524 Cation efflux protein	7	14
180	IPR000024 Frizzled cysteine-rich domain	18	304	430	IPR001382 Glycoside hydrolase, family 47	7	53
181	IPR001199 Cytochrome b5	18	183	431	IPR004825 Insulin/IGF/relaxin	7	61
182	IPR001878 Zinc finger, CCHC-type	18	120	432	IPR001984 Peptidase S16, Lon protease	7	57
183	IPR000859 CUB	18	246	433	IPR000756 Diacylglycerol kinase accessory region	7	150
184	IPR001844 Chaperonin Cpn60	18	221	434	IPR000387 Protein-tyrosine phosphatase	7	50
185	IPR000348 emp24/gp25L/p24	17	83	435	IPR001876 Zinc finger, RanBP2-type	7	54
186	IPR000337 GPCR, family 3	17	237	436	IPR000582 Acyl-CoA-binding protein, ACBP	7	62
187	IPR000717 Proteasome component region PCI	17	49	437	IPR010625 CHCH	7	10
188	IPR002659 Glycosyl transferase, family 31	17	21	438	IPR002350 Proteinase inhibitor I1, Kazal	7	54
189	IPR000421 Coagulation factor 5/8 type, C-terminal	17	891	439	IPR002495 Glycosyl transferase, family 8	7	8
190	IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit	17	333	440	IPR006680 Amidohydrolase 1	7	20
191	IPR002017 Spectrin repeat	17	169	441	IPR005301 Mob1/phocein	7	18
192	IPR000413 Integrins alpha chain	17	427	442	IPR006977 Yip1 domain	7	8
193	IPR001148 Carbonic anhydrase, eukaryotic	17	66	443	IPR001873 Na+ channel, amiloride-sensitive	7	95
194	IPR000827 Small chemokine, C-C group, conserved site	17	107	444	IPR003859 Metazoa galactosyltransferase	7	9
195	IPR001675 Glycosyl transferase, family 29	17	40	445	IPR000239 GPCR kinase	7	148
196	IPR000463 Cytosolic fatty-acid binding	17	97	446	IPR003533 Doublecortin	7	30
197	IPR000804 Clathrin adaptor, sigma subunit/coatomer, zeta subunit	17	111	447	IPR003137 Protease-associated PA	7	21
198	IPR001368 TNFR/CD27/30/40/95 cysteine-rich region	17	121	448	IPR002314 Aminoacyl-tRNA synthetase, class II (G, H, P and S)	7	89
199	IPR001124 Lipid-binding serum glycoprotein	16	44	449	IPR001799 Ephrin	7	64
200	IPR003599 Immunoglobulin subtype	16	53	450	IPR002328 Alcohol dehydrogenase, zinc-containing, conserved site	7	39
201	IPR002130 Peptidyl-prolyl cis-trans isomerase, cyclophilin-type	16	149	451	IPR011021 Arrestin-like, N-terminal	7	28
202	IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding	16	324	452	IPR005076 Glycosyl transferase, family 6	7	9
203	IPR000425 Major intrinsic protein	16	136	453	IPR001223 Glycoside hydrolase, family 18, catalytic domain	7	43
204	IPR000001 Kringle	16	553	454	IPR000034 Laminin B	7	815
205	IPR002494 Keratin, high sulphur B2 protein	16	27	455	IPR007053 NC	7	13
206	IPR013216 Methyltransferase type 11	16	36	456	IPR003663 Sugar transporter	7	65
207	IPR000920 Myelin P0 protein	16	278	457	IPR000620 Protein of unknown function DUF6, transmembrane	7	13
208	IPR008197 Whey acidic protein, 4-disulphide core	16	146	458	IPR000532 Glucagon/GIP/secretin/VIP	7	51
209	IPR004031 PMP-22/EMP/MP20/Claudin	16	130	459	IPR000997 Cholinesterase	7	75
210	IPR001487 Bromodomain	16	326	460	IPR004012 RUN	7	21
211	IPR001320 Ionotropic glutamate receptor	15	134	461	IPR003092 Potassium channel, two pore-domain, TASK	7	154
212	IPR001770 G-protein, gamma subunit	15	119	462	IPR001152 Thymosin beta-4	7	25
213	IPR002209 Heparin-binding growth factor/Fibroblast growth factor	15	191	463	IPR003080 Glutathione S-transferase, alpha class	7	62
214	IPR001400 Somatotropin hormone	15	124	464	IPR001429 P2X purinoreceptor	7	159
215	IPR001357 BRCT	15	257	465	IPR002075 Nuclear transport factor 2	7	22
216	IPR000837 Fos transforming protein	15	239	466	IPR001372 Dynein light chain, type 1 and 2	7	16
217	IPR003347 Transcription factor jumonji/aspartyl beta-hydroxylase	15	49	467	IPR000009 Protein phosphatase 2A, regulatory subunit PR55	7	204
218	IPR000644 Cystathionine beta-synthase, core	15	182	468	IPR001312 Hexokinase	7	91
219	IPR001194 DENN	15	154	469	IPR005819 Histone H5	7	21
220	IPR013026 Tetratricopeptide region	15	57	470	IPR003323 Ovarian tumour, otubain	7	25
221	IPR000917 Sulphatase	15	85	471	IPR007604 CP2 transcription factor	7	12
222	IPR002123 Phospholipid/glycerol acyltransferase	15	37	472	IPR000432 DNA mismatch repair protein MutS, C-terminal	7	138
223	IPR000209 Peptidase S8 and S53, subtilisin, kexin, sedolisin	15	215	473	IPR001431 Peptidase M16, zinc-binding site	7	51
224	IPR001023 Heat shock protein Hsp70	14	138	474	IPR005522 Inositol polyphosphate kinase	7	8
225	IPR000433 Zinc finger, ZZ-type	14	244	475	IPR000687 RIO kinase	7	76
226	IPR001315 Caspase Recruitment	14	103	476	IPR012496 TMC	7	8
227	IPR004827 Basic-leucine zipper (bZIP) transcription factor	14	59	477	IPR001932 Protein phosphatase 2C-related	7	31
228	IPR000183 Orn/DAP/Arg decarboxylase 2	14	281	478	IPR000006 Metallothionein, vertebrate	7	57
229	IPR000095 PAK-box/P21-Rho-binding	14	207	479	IPR000850 Adenylate kinase	7	61
230	IPR006020 Phosphotyrosine interaction region	14	50	480	IPR003081 Glutathione S-transferase, Mu class	7	70
231	IPR002394 Nicotinic acetylcholine receptor, N-terminal	14	255	481	IPR001071 Cellular retinaldehyde binding/alpha-tocopherol transport	7	72
232	IPR000562 Type II fibronectin, collagen-binding	14	465	482	IPR008661 L6 membrane	7	8
233	IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II	13	283	483	IPR000974 Glycoside hydrolase, family 22, lysozyme	7	129
234	IPR002917 GTP-binding protein, HSR1-related	13	75	484	IPR002208 SecY protein	7	62
235	IPR001283 Allergen V5/Tpx-1 related	13	155	485	IPR001863 Glypican	7	12
236	IPR007960 Mammalian taste receptor	13	14	486	IPR002610 Peptidase S54, rhomboid	7	17
237	IPR001179 Peptidyl-prolyl cis-trans isomerase, FKBP-type	13	55	487	IPR013057 Amino acid transporter, transmembrane	6	6
238	IPR000716 Thyroglobulin type-1	13	206	488	IPR004301 Nucleoplasmin	6	20
239	IPR000038 Cell division/GTP binding protein	13	83	489	IPR002087 Anti-proliferative protein	6	48
240	IPR004295 Env gp36 protein, HERV/MMTV type	13	14	490	IPR007951 PMG	6	6
241	IPR001388 Synaptobrevin	13	101	491	IPR005679 Ribosomal protein S12, bacterial-type	6	51
242	IPR002957 Keratin, type I	13	99	492	IPR008979 Galactose-binding like	6	11
243	IPR001279 Beta-lactamase-like	13	22	493	IPR001894 Cathelicidin	6	12
244	IPR000560 Histidine acid phosphatase	13	126	494	IPR000096 Serum amyloid A protein	6	54
245	IPR001089 Small chemokine, C-X-C	13	147	495	IPR001778 Pollen allergen Poa pIX/Phl pVI, C-terminal	6	38
246	IPR000956 Stathmin	13	78	496	IPR007194 Transport protein particle (TRAPP) component, Bet3	6	9
247	IPR000116 High mobility group proteins HMG-I and HMG-Y	13	206	497	IPR001593 Ribosomal protein S3Ae	6	15
248	IPR000569 HECT	13	184	498	IPR002395 HMW kininogen	6	23
249	IPR001063 Ribosomal protein L22/L17	13	65	499	IPR000407 Nucleoside phosphatase GDA1/CD39	6	14
250	IPR001270 Chaperonin clpA/B	12	102	500	IPR000434 Polycystic kidney disease type 1 protein	6	131

View top 40 InterPro hits

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